LiveSpo Spore Probiotics are renowned for their superior pharmacodynamic properties in comparison with other forms of probiotics. Several key factors contribute to their exceptional effectiveness and therapeutic benefits are as follows.
Spore probiotic strains
One primary aspect that sets LiveSpo Spore Probiotics apart is the presence of Bacillus sp. spores. These spores, although not native residents of the gut microflora, have been depth and extensively studied by LiveSpo Pharma Co. Ltd., including their whole genome, and physiological and biochemical characteristics. They are entirely non-pathogenic and possess numerous beneficial properties. When administered orally, these spores display a remarkable ability to resist chemical and physical agents, enabling them to traverse the barrier of the acid gastric juices and reach the intestinal tract unharmed.
Once in the small intestines, the spores germinate into metabolically active vegetative cells, allowing them to exert their therapeutic effects. Furthermore, when spraying onto the nasal, dermal, or vaginal area, these spores can adhere to the mucosal and skin, germinate, and exert their therapeutic effects on human health.
How do they function?
LiveSpo Spore Probiotics plays a crucial role in restoring the balance of intestinal microflora. The gut microflora can be influenced by many factors, leading to an imbalance in its composition (called dysbiosis). However, Bacillus sp. spores in LiveSpo Spore Probiotics products contribute to the recovery and normalization of the intestinal microflora, promoting overall gut health.
Bacillus Spore Probiotics Biofilm
Additionally, Bacillus sp. spores can produce several vitamins, particularly group B vitamins. This capacity becomes particularly significant when correcting a vitaminosis caused by antibiotics and chemotherapeutic agents. By providing an additional source of essential vitamins, LiveSpo Spore Probiotics help counteract the potential vitamin deficiencies associated with these medications.
Moreover, the Bacillus sp. spores in LiveSpo Spore Probiotic products can adsorb toxins, and inhibit or kill harmful bacteria and viruses. Additionally, they produce a diverse array of antimicrobial compounds closely associated with the metabolic activity of the Bacillus sp. spores. This notable characteristic allows LiveSpo Spore Probiotics to provide a broader range of therapeutic benefits beyond restoring intestinal microflora.
Furthermore, LiveSpo Spore Probiotics exhibit resistance to various antibiotics, providing a basis for preventing any harmful alteration of the intestinal microflora caused by the potential side effects of antibiotics. The ability of LiveSpo Spore Probiotics to withstand the impact of antibiotics allows them to be administered concurrently or in the interval between antibiotic doses, thereby helping to preserve the balance of the intestinal microflora.
Scientific Validation of LiveSpo Spore Probiotics’ Pioneering Health Benefits
With Gastrointestinal Health
Scientific pieces of evidence support the superior pharmacodynamic properties of LiveSpo Spore Probiotics. The study conducted by Binh NT et al. (2021) has demonstrated that LiveSpo Spore Probiotics (specifically, LiveSpo® Colon) are safe and effective in providing supportive treatment for Inflammatory Bowel Disease (IBD), including Crohn’s disease and ulcerative colitis. In 2022, a study by My TT et al. indicated that LiveSpo Spore Probiotics, specifically LiveSpo® Clausy, display resistance to extremely high temperatures and acidic conditions (low pH2).
These probiotics have long-term stability with viability maintenance for at least 24 months at room temperature, making them suitable for use as a food supplement [1]. Moreover, the study’s results have demonstrated that LiveSpo Spore Probiotics have the ability to enhance the growth of beneficial bacteria in the intestinal tract while inhibiting the proliferation of harmful bacteria.
With Respiratory Health
These findings were observed in a rabbit model, providing evidence for the therapeutic potential of LiveSpo Spore Probiotics in promoting healthy gut microbiota. Additionally, in 2022, Dien TM et al. conducted the first randomized and bind clinical trial in Respiratory Syncytial Virus (RSV) infected children and demonstrated the safety and beneficial effects of nasal-spraying Bacillus spore probiotics (LiveSpo® Navax) in the supportive treatment of Acute Respiratory Tract Infections (ARTIs).
The study has demonstrated that LiveSpo® Navax can promptly and effectively alleviate RSV-induced ARTI symptoms revealing a significant reduction in viral load and inflammation. The overall data indicate that LiveSpo® Navax can effectively shorten the treatment and hospitalization time for patients with RSV infection, lower the cost of antibiotic treatment for co-infected bacteria, and reduce the risk of over-expression of cytokines in the nasal tract, which is called “cytokine storm”. [2].
In conclusion, LiveSpo Spore Probiotics possess superior pharmacodynamic properties compared to other forms of traditional probiotics with the ability of resistance to harsh conditions; ability to restore the balance of intestinal microflora; capacity for vitamin production, antitoxic action, and antibiotic resistance collectively. Through these unique attributes, LiveSpo Spore Probiotics offer a highly effective and potential solution for maintaining gut health and managing various human health conditions.
References
- My TT, D.L., Lien NT, Anh VNT, Anh NH, Stability and safety study of liquid-suspension Bacillus clausii spore probiotics (Livespo Clausy). Tạp Chí Nghiên cứu Y học, 2022. 154(6): p. 10-19.
- Tran, D.M., et al., Nasal-spraying Bacillus spores as an effective symptomatic treatment for children with acute respiratory syncytial virus infection. Scientific Reports, 2022. 12(1): p. 12402.
